Impact of CDKN2A/B, MTAP, and TERT Genetic Alterations on Survival in IDH Wild Type Glioblastomas

Impact of CDKN2A/B, MTAP, and TERT Genetic Alterations on Survival in IDH Wild Type Glioblastomas

Abstract Purpose Poor outcomes in IDH wild-type (IDHwt) glioblastomas indicate the need to determine which genetic alterations can indicate poor survival and guidance of patient specific treatment options. We sought to identify the genetic alterations in these patients that predict for survival when...

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Bibliographic Details
Main Authors: Eric J. Hsu, Jamie Thomas, Elizabeth A. Maher, Michael Youssef, Robert D. Timmerman, Zabi Wardak, Tu D. Dan, Toral R. Patel, Dat T. Vo
Format: Article
Language:English
Published: Springer 2022-11-01
Series:Discover Oncology
Subjects:
Next generation sequencing
WHO CNS5
Glioblastoma
CDKN2A
TERT
Radiation therapy
Online Access:https://doi.org/10.1007/s12672-022-00590-2

Internet

https://doi.org/10.1007/s12672-022-00590-2

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