In Silico Prediction and Design of Uropathogenic <i>Escherichia coli</i> Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin

In Silico Prediction and Design of Uropathogenic <i>Escherichia coli</i> Alpha-Hemolysin Generate a Soluble and Hemolytic Recombinant Toxin

The secretion of α-hemolysin by uropathogenic <i>Escherichia coli</i> (UPEC) is commonly associated with the severity of urinary tract infections, which makes it a predictor of poor prognosis among patients. Accordingly, this toxin has become a target for diagnostic tests and therapeutic...

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Bibliographic Details
Main Authors: Bruna De Lucca Caetano, Marta de Oliveira Domingos, Miriam Aparecida da Silva, Jessika Cristina Alves da Silva, Juliana Moutinho Polatto, Fabio Montoni, Leo Kei Iwai, Daniel Carvalho Pimenta, Hugo Vigerelli, Paulo Cesar Gomes Vieira, Rita de Cassia Ruiz, José Salvatore Patané, Roxane Maria Fontes Piazza
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Microorganisms
Subjects:
bacterial toxins
uropathogenic <i>Escherichia coli</i>
alpha-hemolysin
in silico prediction
Online Access:https://www.mdpi.com/2076-2607/10/1/172

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https://www.mdpi.com/2076-2607/10/1/172

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