Isolation and Proteomics of the Insulin Secretory Granule

Insulin, a vital hormone for glucose homeostasis is produced by pancreatic beta-cells and when secreted, stimulates the uptake and storage of glucose from the blood. In the pancreas, insulin is stored in vesicles termed insulin secretory granules (ISGs). In Type 2 diabetes (T2D), defects in insulin...

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Bibliographic Details
Main Authors: Nicholas Norris, Belinda Yau, Melkam Alamerew Kebede
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/5/288