Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors.

Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors.

The continued burden of HIV in resource-limited regions such as parts of sub-Saharan Africa, combined with adverse effects and potential risks of resistance to existing antiretroviral therapies, emphasize the need to identify new HIV inhibitors. Here we performed a virtual screen of molecules from t...

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Bibliographic Details
Main Authors: Ian Tietjen, Fidele Ntie-Kang, Philip Mwimanzi, Pascal Amoa Onguéné, Margaret A Scull, Thomas Oyebode Idowu, Abiodun Oguntuga Ogundaini, Luc Mbaze Meva'a, Berhanu M Abegaz, Charles M Rice, Kerstin Andrae-Marobela, Mark A Brockman, Zabrina L Brumme, David Fedida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4382154?pdf=render

Internet

http://europepmc.org/articles/PMC4382154?pdf=render

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