Expression of cytotoxic mediators (perforin, granzyme B, FAS, and FAS-l) in renal allograft biopsies

Objectives: To analyze the in situ expression of perforin, granzymeB, FAS-L and FAS in renal allograft biopsies by means ofimmunohistochemistry and correlate these findings with the degreeof histologic rejection and allograft outcome. Methods: Ninety-sixallograft biopsies were divided into three gro...

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Main Authors: Therezinha Gauri Leitão, Luís Eduardo Becker, Ivone Braga de Oliveira, Flávia Ramos de Siqueira, Maria Regina Teixeira Araújo, João Egídio Romão Junior, Hugo Abensur, Irene de Lourdes Noronha
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2006-12-01
Series:Einstein (São Paulo)
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Online Access:http://www.einstein.br/revista/arquivos/PDF/Einstein_vol4_n4_2006_p277.pdf