α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes.

α-Thalassemia results from decreased production of α-globin chains that make up part of hemoglobin tetramers (Hb; α(2)β(2)) and affects up to 50% of individuals in some regions of sub-Saharan Africa. Heterozygous (-α/αα) and homozygous (-α/-α) genotypes are associated with reduced risk of severe Pla...

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Bibliographic Details
Main Authors:	Michael A Krause, Seidina A S Diakite, Tatiana M Lopera-Mesa, Chanaki Amaratunga, Takayuki Arie, Karim Traore, Saibou Doumbia, Drissa Konate, Jeffrey R Keefer, Mahamadou Diakite, Rick M Fairhurst
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3356384?pdf=render

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http://europepmc.org/articles/PMC3356384?pdf=render

α-Thalassemia impairs the cytoadherence of Plasmodium falciparum-infected erythrocytes.

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