Identification of (24E)-3 alpha,7 alpha-dihydroxy-5 beta-cholest-24-enoic acid and (24R,25S)-3 alpha,7 alpha,24-trihydroxy-5 beta-cholestanoic acid as intermediates in the conversion of 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid to chenodeoxycholic acid in rat liver homogenates.
Studies of chemical structure of the intermediates in the biosynthetic sequence between 3 alpha,7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) and chenodeoxycholic acid have been undertaken. Radiolabeled DHCA was incubated with a rat liver preparation. The reaction products were converted to the...
| Glavni autori: | , , , , |
|---|---|
| Format: | Članak |
| Jezik: | English |
| Izdano: |
Elsevier
1994-04-01
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| Serija: | Journal of Lipid Research |
| Online pristup: | http://www.sciencedirect.com/science/article/pii/S0022227520411757 |