Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro

Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro

Background: The treatment of grafts with vancomycin for ligament reconstruction in knee surgery is the current standard. However, high antibiotic concentrations have chondrotoxic effects. Purpose: To test the chondrotoxicity of clindamycin, gentamicin and vancomycin in comparable concentrations. In...

Full description

Bibliographic Details
Main Authors: Hermann O. Mayr, Nina Regenbrecht, Moritz Florian Mayr, Bianca Riedel, Melanie L. Hart, Hagen Schmal, Michael Seidenstuecker
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
chondrotoxicity of antibiotics
infection prophylaxis
ligament surgery
concentration of antibiotics
LDH test
WST-1 test
Online Access:https://www.mdpi.com/2227-9059/11/12/3143

Internet

https://www.mdpi.com/2227-9059/11/12/3143

Similar Items