Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro

Effect of Vancomycin, Gentamicin and Clindamycin on Cartilage Cells In Vitro

Background: The treatment of grafts with vancomycin for ligament reconstruction in knee surgery is the current standard. However, high antibiotic concentrations have chondrotoxic effects. Purpose: To test the chondrotoxicity of clindamycin, gentamicin and vancomycin in comparable concentrations. In...

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Bibliographic Details
Main Authors:	Hermann O. Mayr, Nina Regenbrecht, Moritz Florian Mayr, Bianca Riedel, Melanie L. Hart, Hagen Schmal, Michael Seidenstuecker
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Biomedicines
Subjects:	chondrotoxicity of antibiotics infection prophylaxis ligament surgery concentration of antibiotics LDH test WST-1 test
Online Access:	https://www.mdpi.com/2227-9059/11/12/3143

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