Current Landscape of NRF2 Biomarkers in Clinical Trials

The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by <i>NFE2L2</i>) plays a critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the regulation of inflammation and cellular detoxication pathways. The contribution of the NRF2 pathway to...

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Bibliographic Details
Main Authors: Yoko Yagishita, Tonibelle N. Gatbonton-Schwager, Melissa L. McCallum, Thomas W. Kensler
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/8/716