Toxicarioside A inhibits tumor growth and angiogenesis: involvement of TGF-β/endoglin signaling.

Toxicarioside A is a cardenolide isolated mainly from plants and animals. Emerging evidence demonstrate that cardenolides not only have cardiac effects but also anticancer effects. In this study, we used in vivo models to investigate the antitumor activities of toxicarioside A and the potential mech...

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Main Authors: Feng-Ying Huang, Wen-Li Mei, Yue-Nan Li, Guang-Hong Tan, Hao-Fu Dai, Jun-Li Guo, Hua Wang, Yong-Hao Huang, Huan-Ge Zhao, Song-Lin Zhou, Ying-Ying Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3508932?pdf=render