Revealing the Therapeutic Potential of Botulinum Neurotoxin Type A in Counteracting Paralysis and Neuropathic Pain in Spinally Injured Mice

Revealing the Therapeutic Potential of Botulinum Neurotoxin Type A in Counteracting Paralysis and Neuropathic Pain in Spinally Injured Mice

Botulinum neurotoxin type A (BoNT/A) is a major therapeutic agent that has been proven to be a successful treatment for different neurological disorders, with emerging novel therapeutic indications each year. BoNT/A exerts its action by blocking SNARE complex formation and vesicle release through th...

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Bibliographic Details
Main Authors: Valentina Vacca, Luca Madaro, Federica De Angelis, Daisy Proietti, Stefano Cobianchi, Tiziana Orsini, Pier Lorenzo Puri, Siro Luvisetto, Flaminia Pavone, Sara Marinelli
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Toxins
Subjects:
botulinum neurotoxin type A
glial scar
spinal cord injury
neuropathic pain
neurodegeneration
paralysis
Online Access:https://www.mdpi.com/2072-6651/12/8/491

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https://www.mdpi.com/2072-6651/12/8/491

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