Identification of Genetic Mutations in Cancer: Challenge and Opportunity in the New Era of Targeted Therapy

Identification of Genetic Mutations in Cancer: Challenge and Opportunity in the New Era of Targeted Therapy

The introduction of targeted therapy is the biggest success in the treatment of cancer in the past few decades. However, heterogeneous cancer is characterized by diverse molecular alterations as well as multiple clinical profiles. Specific genetic mutations in cancer therapy targets may increase dru...

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Bibliographic Details
Main Authors: Jing Jin, Xu Wu, Jianhua Yin, Mingxing Li, Jing Shen, Jing Li, Yueshui Zhao, Qijie Zhao, Jingbo Wu, Qinglian Wen, Chi Hin Cho, Tao Yi, Zhangang Xiao, Liping Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Oncology
Subjects:
targeted therapy
cyclin-dependent kinases 4/6
somatic mutation
resistance
EGFR
PD-1/PD-L1
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00263/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00263/full

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