Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations

Heterogeneity of Cellular Senescence: Cell Type-Specific and Senescence Stimulus-Dependent Epigenetic Alterations

The aim of the present study was to provide a comprehensive characterization of whole genome DNA methylation patterns in replicative and ionizing irradiation- or doxorubicin-induced premature senescence, exhaustively exploring epigenetic modifications in three different human cell types: in somatic...

Full description

Bibliographic Details
Main Authors: Katarzyna Malgorzata Kwiatkowska, Eleni Mavrogonatou, Adamantia Papadopoulou, Claudia Sala, Luciano Calzari, Davide Gentilini, Maria Giulia Bacalini, Daniele Dall’Olio, Gastone Castellani, Francesco Ravaioli, Claudio Franceschi, Paolo Garagnani, Chiara Pirazzini, Dimitris Kletsas
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cells
Subjects:
replicative senescence
stress-induced premature senescence
methylation
epigenetics
human fibroblasts
mesenchymal stem cells
Online Access:https://www.mdpi.com/2073-4409/12/6/927

Internet

https://www.mdpi.com/2073-4409/12/6/927

Similar Items