Localized accumulation of Xist RNA in X chromosome inactivation
The non-coding RNA Xist regulates the process of X chromosome inactivation, in which one of the two X chromosomes present in cells of early female mammalian embryos is selectively and coordinately shut down. Remarkably Xist RNA functions in cis, affecting only the chromosome from which it is transcr...
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Format: | Article |
Language: | English |
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The Royal Society
2019-12-01
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Series: | Open Biology |
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Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190213 |