Integrated microbiome and metabolome analysis reveals a distinct microbial and metabolic signature in Graves' disease and hypothyroidism

Integrated microbiome and metabolome analysis reveals a distinct microbial and metabolic signature in Graves' disease and hypothyroidism

Recent studies reveal that imbalanced microbiota is related to thyroid diseases. However, studies on the alterations in fecal metabolites in Graves' disease and clinical hypothyroidism patients are insufficient. Here, we identified 21 genera and 53 metabolites that were statistically significan...

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Bibliographic Details
Main Authors: Wen Jiang, Ganghua Lu, Tingting Qiao, Xiaqing Yu, Qiong Luo, Junyu Tong, Suyun Fan, Li Chai, Dingwei Gao, Ru Wang, Chengwen Deng, Zhongwei Lv, Dan Li
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Subjects:
Graves' disease
Clinical hypothyroidism
Microbiota
16S rRNA gene sequencing
Non-targeted metabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023086711

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http://www.sciencedirect.com/science/article/pii/S2405844023086711

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