Muscle PGC-1α modulates hepatic mitophagy regulation during aging

Muscle PGC-1α modulates hepatic mitophagy regulation during aging

Aging has been suggested to be associated with changes in oxidative capacity, autophagy, and mitophagy in the liver, but a simultaneous evaluation of these key cellular processes is lacking. Moreover, skeletal muscle transcriptional coactivator peroxisome proliferator-activated receptor gamma coacti...

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Bibliographic Details
Main Authors: Natascha Masselkhi Christensen, Stine Ringholm, Bjørg Thiellesen Buch, Anders Gudiksen, Jens Frey Halling, Henriette Pilegaard
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Experimental Gerontology
Subjects:
Liver
Metabolism
Autophagy
Parkin
Aging
PGC-1α
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556522003552

Internet

http://www.sciencedirect.com/science/article/pii/S0531556522003552

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