Chronic Propafenone Application Increases Functional K<sub>IR</sub>2.1 Expression In Vitro

Chronic Propafenone Application Increases Functional K<sub>IR</sub>2.1 Expression In Vitro

Expression and activity of inwardly rectifying potassium (K<sub>IR</sub>) channels within the heart are strictly regulated. K<sub>IR</sub> channels have an important role in shaping cardiac action potentials, having a limited conductance at depolarized potentials but contribu...

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Bibliographic Details
Main Authors: Encan Li, Willy Kool, Liset Woolschot, Marcel A. G. van der Heyden
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
K<sub>IR</sub>2.1
AgoKir
long-term effects
propafenone
trafficking
Online Access:https://www.mdpi.com/1424-8247/16/3/404

Internet

https://www.mdpi.com/1424-8247/16/3/404

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