AATF inhibition exerts antiangiogenic effects against human hepatocellular carcinoma

AATF inhibition exerts antiangiogenic effects against human hepatocellular carcinoma

Background and aimsAngiogenesis is a key factor in the growth and metastasis of hepatic tumors and thus a potential therapeutic target in hepatocellular carcinoma (HCC). In this study, we aim to identify the key role of apoptosis antagonizing transcription factor (AATF) in tumor angiogenesis and its...

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Bibliographic Details
Main Authors: Diwakar Suresh, Akshatha N. Srinivas, Akila Prashant, Suchitha Satish, Prashant Vishwanath, Suma M. Nataraj, Srinivas V. Koduru, Prasanna K. Santhekadur, Divya P. Kumar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
apoptosis antagonizing transcription factor
angiogenesis
hepatocellular carcinoma
knockdown (KD)
human umbilic vein endothelial cells (HUVEC)
pigment epithelium derived factor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1130380/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1130380/full

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