Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells

Abstract Mesenchymal stem/Stromal cells (MSCs) have great therapeutic potentials, and they have been isolated from various tissues and organs including definitive endoderm (DE) organs, such as the lung, liver and intestine. MSCs have been induced from human pluripotent stem cells (hPSCs) through mul...

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Bibliographic Details
Main Authors: Yumeng Zhang, Ye Yi, Xia Xiao, Lingling Hu, Jiaqi Xu, Dejin Zheng, Ho Cheng Koc, Un In Chan, Ya Meng, Ligong Lu, Weiwei Liu, Xiaoling Xu, Ningyi Shao, Edwin Chong Wing Cheung, Ren-He Xu, Guokai Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04810-5