Efficacy and safety of left atrial appendage closure compared with oral anticoagulation in atrial fibrillation: a meta-analysis of randomized controlled trials and propensity-matched studies

Efficacy and safety of left atrial appendage closure compared with oral anticoagulation in atrial fibrillation: a meta-analysis of randomized controlled trials and propensity-matched studies

BackgroundsTwo recent randomized controlled trials (RCTs), the PROTECT-AF and the PREVAIL, showed that in atrial fibrillation (AF) patients, left atrial appendage closure (LAAC) is comparable to oral anticoagulants (OAC) in the prevention of stroke and could also possibly reduce mortality. Neverthel...

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Bibliographic Details
Main Authors: Luca Franchin, Francesco Piroli, Pierluigi Demola, Francesca Mantovani, Mario Iannaccone, Roberto Manfredi, Fabrizio D’Ascenzo, Federico Fortuni, Fabrizio Ugo, Francesco Meucci, Alessandro Navazio, Giacomo Boccuzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atrial fibrillation
left atrial appendage closure
oral anticoagulation
meta-analysis
cardiovascular intervention
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1212161/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1212161/full

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