Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphoma

Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphoma

Summary: To understand the clinical significance of the tumor microenvironment (TME), it is essential to study the interactions between malignant and non-malignant cells in clinical specimens. Here, we established a computational framework for a multiplex imaging system to comprehensively characteri...

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Bibliographic Details
Main Authors: Margaretha G.M. Roemer, Tim van de Brug, Erik Bosch, Daniella Berry, Nathalie Hijmering, Phylicia Stathi, Karin Weijers, Jeannette Doorduijn, Jacoline Bromberg, Mark van de Wiel, Bauke Ylstra, Daphne de Jong, Yongsoo Kim
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:iScience
Subjects:
Oncology
Neuroscience
Cell biology
Mathematical biosciences
Computational bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223014086

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http://www.sciencedirect.com/science/article/pii/S2589004223014086

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