Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis

Rare CYLD Variants in Chinese Patients With Amyotrophic Lateral Sclerosis

Background: CYLD Lysine 63 Deubiquitinase gene (CYLD) was recently identified to be a novel causative gene for frontal temporal dementia (FTD)-amyotrophic lateral sclerosis (ALS). In the current study, we aimed to (1) systematically screen the mutations of CYLD in a large cohort of Chinese ALS patie...

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Bibliographic Details
Main Authors: Xiaojing Gu, Yongping Chen, Qianqian Wei, Yanbing Hou, Bei Cao, Lingyu Zhang, Ruwei Ou, Junyu Lin, Kuncheng Liu, Bi Zhao, Huifang Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
CYLD lysine 63 deubiquitinase gene
amyotrophic lateral sclerosis
mutation screening
phenotype
burden analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.740052/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.740052/full

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