MicroRNAs can regulate human APP levels

<p>Abstract</p> <p>A number of studies have shown that increased APP levels, resulting from either a genomic locus duplication or alteration in <it>APP </it>regulatory sequences, can lead to development of early-onset dementias, including Alzheimer's disease (AD)....

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Bibliographic Details
Main Authors: Rogers Jack T, Huang Qihong, Ansaloni Sara, Miller Nathan, Hoang David, Patel Neha, Lee Jeremy C, Saunders Aleister J
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/3/1/10