MicroRNAs can regulate human APP levels
<p>Abstract</p> <p>A number of studies have shown that increased APP levels, resulting from either a genomic locus duplication or alteration in <it>APP </it>regulatory sequences, can lead to development of early-onset dementias, including Alzheimer's disease (AD)....
Main Authors: | Rogers Jack T, Huang Qihong, Ansaloni Sara, Miller Nathan, Hoang David, Patel Neha, Lee Jeremy C, Saunders Aleister J |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-08-01
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Series: | Molecular Neurodegeneration |
Online Access: | http://www.molecularneurodegeneration.com/content/3/1/10 |
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