Depletion of intracellular Ca2+ induces FOXM1 SUMOylation and accumulation on the inner nuclear membrane and accelerates G2/M cell cycle transition

Depletion of intracellular Ca2+ induces FOXM1 SUMOylation and accumulation on the inner nuclear membrane and accelerates G2/M cell cycle transition

Intracellular calcium (Ca2+) has been reported to regulate transcription factor activity and cancer development, but how it affects the function of Forkhead box protein M1 (FOXM1), a crucial transcription factor and key oncogene participating in tumorigenesis, remains unclear. Here, we investigated...

Full description

Bibliographic Details
Main Authors: Tzu-Chien Lin, Ping-Jung Chung, Chen-An Shen, Thi My Hang Nguyen, Yi-Syuan Lin, Shih-Chieh Lin, Shih-Chuan Hsiao, Wen-Tai Chiu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:European Journal of Cell Biology
Subjects:
Calcium
FOXM1
Inner nuclear membrane
SUMOylation
Cell cycle
Online Access:http://www.sciencedirect.com/science/article/pii/S017193352300047X

Internet

http://www.sciencedirect.com/science/article/pii/S017193352300047X

Similar Items