LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1

Abstract Purpose Papillary thyroid cancer (PTC) is the most common endocrine malignancy with a fast-growing incidence in recent decades. HOTAIR as a long non-coding RNA has been shown to be highly expressed in papillary thyroid cancer tissues with only a limited understanding of its functional roles...

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Main Authors: Feng-Chih Kuo, Yu-Ting Wang, Chia-Hsin Liu, Yao-Feng Li, Chieh-Hua Lu, Sheng-Chiang Su, Jhih-Syuan Liu, Peng-Fei Li, Chia-Luen Huang, Li-Ju Ho, Chien-Ming Lin, Chien-Hsing Lee
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02817-2