LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1

LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1

Abstract Purpose Papillary thyroid cancer (PTC) is the most common endocrine malignancy with a fast-growing incidence in recent decades. HOTAIR as a long non-coding RNA has been shown to be highly expressed in papillary thyroid cancer tissues with only a limited understanding of its functional roles...

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Main Authors: Feng-Chih Kuo, Yu-Ting Wang, Chia-Hsin Liu, Yao-Feng Li, Chieh-Hua Lu, Sheng-Chiang Su, Jhih-Syuan Liu, Peng-Fei Li, Chia-Luen Huang, Li-Ju Ho, Chien-Ming Lin, Chien-Hsing Lee
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
lncRNA
HOTAIR
Papillary thyroid cancer
DLX1
Online Access:https://doi.org/10.1186/s12935-022-02817-2

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