The promoting effect and mechanism of MAD2L2 on stemness maintenance and malignant progression in glioma

Abstract Background Glioblastoma, the most common primary malignant tumor of the brain, is associated with poor prognosis. Glioblastoma cells exhibit high proliferative and invasive properties, and glioblastoma stem cells (GSCs) have been shown to play a crucial role in the malignant behavior of gli...

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Bibliographic Details
Main Authors: Zhiyuan Liu, Songtao Wang, Kuo Yu, Kaile Chen, Liang Zhao, Jiayue Zhang, Kexiang Dai, Peng Zhao
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04740-0