In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

Abstract CXCR4 is a G‐protein‐coupled receptor that mediates recruitment of blood cells toward its ligand SDF‐1. In cancer, high CXCR4 expression is frequently associated with tumor dissemination and poor prognosis. We evaluated the novel CXCR4 probe [68Ga]Pentixafor for in vivo mapping of CXCR4 exp...

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Bibliographic Details
Main Authors: Kathrin Philipp‐Abbrederis, Ken Herrmann, Stefan Knop, Margret Schottelius, Matthias Eiber, Katharina Lückerath, Elke Pietschmann, Stefan Habringer, Carlos Gerngroß, Katharina Franke, Martina Rudelius, Andreas Schirbel, Constantin Lapa, Kristina Schwamborn, Sabine Steidle, Elena Hartmann, Andreas Rosenwald, Saskia Kropf, Ambros J Beer, Christian Peschel, Hermann Einsele, Andreas K Buck, Markus Schwaiger, Katharina Götze, Hans‐Jürgen Wester, Ulrich Keller
Format: Article
Language:English
Published: Springer Nature 2015-03-01
Series:EMBO Molecular Medicine
Subjects:
chemokine receptor
CXCR4
in vivo imaging
multiple myeloma
positron emission tomography
Online Access:https://doi.org/10.15252/emmm.201404698

Internet

https://doi.org/10.15252/emmm.201404698

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