Safety Study of an Original Mesenchymal Stromal Cell Secretome-Based Medicinal Product for Spermatogenesis Restoration

Safety Study of an Original Mesenchymal Stromal Cell Secretome-Based Medicinal Product for Spermatogenesis Restoration

SCIENTIFIC RELEVANCE. Currently, there are no effective and safe medicinal products for idiopathic male infertility. Previous studies in two animal models of infertility (short-term cryptorchidism in rats and doxorubicin-induced testicular injury in mice) have shown the effectiveness of an originato...

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Bibliographic Details
Main Authors: A. O. Monakova, G. D. Sagaradze, V. Yu. Balabanyan, N. A. Basalova, A. A. Matichina, A. A. Matichin, K. L. Kryshen, V. S. Popov, Zh. A. Akopyan, A. Yu. Efimenko
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-04-01
Series:Безопасность и риск фармакотерапии
Subjects:
mesenchymal stromal cells
mesenchymal stromal cell secretome
spermatogenesis
rodents
safety
general toxicity
subchronic toxicity
local toxicity
Online Access:https://www.risksafety.ru/jour/article/view/364

Internet

https://www.risksafety.ru/jour/article/view/364

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