Interplay between path and speed in decision making by high-dimensional stochastic gene regulatory networks.

Induction of a specific transcriptional program by external signaling inputs is a crucial aspect of intracellular network functioning. The theoretical concept of coexisting attractors representing particular genetic programs is reasonably adapted to experimental observations of "genome-wide&quo...

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Bibliographic Details
Main Authors: Nuno R Nené, Alexey Zaikin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398018?pdf=render