Bicyclol Attenuates Liver Inflammation Induced by Infection of Hepatitis C Virus via Repressing ROS-Mediated Activation of MAPK/NF-κB Signaling Pathway

Bicyclol Attenuates Liver Inflammation Induced by Infection of Hepatitis C Virus via Repressing ROS-Mediated Activation of MAPK/NF-κB Signaling Pathway

Treatment with direct-acting antivirals (DAAs) cures most patients infected with hepatitis C virus (HCV) in the real world. However, some patients, especially those with the underlying advanced liver disease, have a limited reduction of liver injury after achieving a sustained viral response (SVR)....

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Bibliographic Details
Main Authors: Hu Li, Jian-Rui Li, Meng-Hao Huang, Jin-Hua Chen, Xiao-Qin Lv, Li-Li Zou, Jia-Li Tan, Biao Dong, Zong-Gen Peng, Jian-Dong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
bicyclol
hepatitis C virus
anti-inflammatory therapy
inflammatory factor
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01438/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01438/full

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