Development of an Orodispersible Film Containing Stabilized Influenza Vaccine

Development of an Orodispersible Film Containing Stabilized Influenza Vaccine

Most influenza vaccines are administered via injection, which is considered as user-unfriendly. Vaccination via oral cavity using an orodispersible film (ODF) might be a promising alternative. To maintain the antigenicity of the vaccine during preparation and subsequent storage of these ODFs, sugars...

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Bibliographic Details
Main Authors: Yu Tian, Yoshita C. Bhide, Herman J. Woerdenbag, Anke L. W. Huckriede, Henderik W. Frijlink, Wouter L. J. Hinrichs, J. Carolina Visser
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
whole inactivated influenza virus vaccine
orodispersible films
stabilization
trehalose
pullulan
β-galactosidase
hemagglutination
Online Access:https://www.mdpi.com/1999-4923/12/3/245

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https://www.mdpi.com/1999-4923/12/3/245

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