RNA binding protein: coordinated expression between the nuclear and mitochondrial genomes in tumors

RNA binding protein: coordinated expression between the nuclear and mitochondrial genomes in tumors

Abstract Mitochondria are the only organelles regulated by two genomes. The coordinated translation of nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), which together co-encode the subunits of the oxidative phosphorylation (OXPHOS) complex, is critical for determining the metabolic plasticity of tu...

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Bibliographic Details
Main Authors: Jiaoyan Ma, Liankun Sun, Weinan Gao, Yang Li, Delu Dong
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Translational Medicine
Subjects:
OXPHOS
Cytoplasmic translation
Mitochondrial translation
Retrograde signals
LLPS
Online Access:https://doi.org/10.1186/s12967-023-04373-3

Internet

https://doi.org/10.1186/s12967-023-04373-3

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