RNA binding protein: coordinated expression between the nuclear and mitochondrial genomes in tumors
Abstract Mitochondria are the only organelles regulated by two genomes. The coordinated translation of nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), which together co-encode the subunits of the oxidative phosphorylation (OXPHOS) complex, is critical for determining the metabolic plasticity of tu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-07-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-023-04373-3 |