Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

The delta opioid receptor (DOR) is a crucial receptor system that regulates pain, mood, anxiety, and similar mental states. DOR agonists, such as SNC80, and DOR-neutral antagonists, such as naltrindole, were developed to investigate the DOR in vivo and as potential therapeutics for pain and depressi...

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Bibliographic Details
Main Authors: Parthasaradhireddy Tanguturi, Vibha Pathak, Sixue Zhang, Omar Moukha-Chafiq, Corinne E. Augelli-Szafran, John M. Streicher
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
delta opioid receptor
inverse agonist
irreversible antagonist
non-competitive antagonist
molecular pharmacology
Online Access:https://www.mdpi.com/1420-3049/26/21/6693

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https://www.mdpi.com/1420-3049/26/21/6693

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