Antibodies against Platelet Factor 4 and Their Associated Pathologies: From HIT/HITT to Spontaneous HIT-Like Syndrome, to COVID-19, to VITT/TTS

Antibodies against Platelet Factor 4 and Their Associated Pathologies: From HIT/HITT to Spontaneous HIT-Like Syndrome, to COVID-19, to VITT/TTS

Antibodies against platelet factor 4 (PF4), a protein released from alpha-granules of activated platelets, may cause a number of pathophysiological conditions. The most commonly known is heparin-induced thrombocytopenia (HIT), which develops in a small proportion of people treated with the anticoagu...

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Bibliographic Details
Main Authors:	Emmanuel J. Favaloro, Leonardo Pasalic, Giuseppe Lippi
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Antibodies
Subjects:	platelet factor 4 antibodies heparin-induced thrombocytopenia vaccine-induced [immune] thrombotic thrombocytopenia thrombotic thrombocytopenia syndrome PF4
Online Access:	https://www.mdpi.com/2073-4468/11/1/7

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