Predicting population coverage of T-cell epitope-based diagnostics and vaccines

<p>Abstract</p> <p>Background</p> <p>T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a response only in individuals that express an MHC molecule capable...

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Bibliographic Details
Main Authors: Newman Mark J, Southwood Scott, Dinh Kenny, Sidney John, Bui Huynh-Hoa, Sette Alessandro
Format: Article
Language:English
Published: BMC 2006-03-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/7/153