Retrospective study on MGMT methylation status and its clinical significance in gliomas

Retrospective study on MGMT methylation status and its clinical significance in gliomas

Background and purpose: Glioma is a common malignant tumor of central nervous system with poor prognosis. Postoperative concurrent chemoradiotherapy with temozolomide (TMZ) is the main treatment for glioma. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter can pred...

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Bibliographic Details
Main Author: JIANG Lin, LIU Qiying, JIA Liqing, ZHANG Jing, CHANG Heng, XUE Tian, REN Min, BAI Qianming, ZHU Xiaoli, ZHOU Xiaoyan
Format: Article
Language:English
Published: Editorial Office of China Oncology 2023-08-01
Series:Zhongguo aizheng zazhi
Subjects:
|glioma|o6 methylguanine dna methyltransferase|double/triple gene conjoint analysis|prognosis|temozolomide
Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/1693553418471-859025032.pdf

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http://www.china-oncology.com/fileup/1007-3639/PDF/1693553418471-859025032.pdf

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