Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones

Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones

New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed for the synthesis of diverse derivatives of...

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Bibliographic Details
Main Authors: Antonia Di Mola, Maximilian Tiffner, Francesco Scorzelli, Laura Palombi, Rosanna Filosa, Paolo De Caprariis, Mario Waser, Antonio Massa
Format: Article
Language:English
Published: Beilstein-Institut 2015-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
asymmetric synthesis
Belliotti (S)-PD 172938
heterocycles
isoindolinones cascade reactions
phase transfer catalysts
Online Access:https://doi.org/10.3762/bjoc.11.279

Internet

https://doi.org/10.3762/bjoc.11.279

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