Glioblastoma hijacks microglial gene expression to support tumor growth

Glioblastoma hijacks microglial gene expression to support tumor growth

Abstract Background Glioblastomas are the most common and lethal primary brain tumors. Microglia, the resident immune cells of the brain, survey their environment and respond to pathogens, toxins, and tumors. Glioblastoma cells communicate with microglia, in part by releasing extracellular vesicles...

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Bibliographic Details
Main Authors: Sybren L. N. Maas, Erik R. Abels, Lieke L. Van De Haar, Xuan Zhang, Liza Morsett, Srinjoy Sil, Joana Guedes, Pritha Sen, Shilpa Prabhakar, Suzanne E. Hickman, Charles P. Lai, David T. Ting, Xandra O. Breakefield, Marike L. D. Broekman, Joseph El Khoury
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Glioblastoma
Glioma
Microglia
Extracellular vesicles
Exosomes
Microvesicles
Online Access:http://link.springer.com/article/10.1186/s12974-020-01797-2

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http://link.springer.com/article/10.1186/s12974-020-01797-2

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