DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation

Cell free DNA is produced through a non-random process. Here, the authors use orientation-aware fragmentation analysis to identify DNA methylation as a regulator of nuclease function.

Bibliographic Details
Main Authors: Yunyun An, Xin Zhao, Ziteng Zhang, Zhaohua Xia, Mengqi Yang, Li Ma, Yu Zhao, Gang Xu, Shunda Du, Xiang’an Wu, Shuowen Zhang, Xin Hong, Xin Jin, Kun Sun
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35959-6