DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation
Cell free DNA is produced through a non-random process. Here, the authors use orientation-aware fragmentation analysis to identify DNA methylation as a regulator of nuclease function.
Main Authors: | Yunyun An, Xin Zhao, Ziteng Zhang, Zhaohua Xia, Mengqi Yang, Li Ma, Yu Zhao, Gang Xu, Shunda Du, Xiang’an Wu, Shuowen Zhang, Xin Hong, Xin Jin, Kun Sun |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-35959-6 |
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