Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

Modulation of Glial Responses by Furanocembranolides: Leptolide Diminishes Microglial Inflammation in Vitro and Ameliorates Gliosis In Vivo in a Mouse Model of Obesity and Insulin Resistance

Neurodegenerative diseases are age-related disorders caused by progressive neuronal death in different regions of the nervous system. Neuroinflammation, modulated by glial cells, is a crucial event during the neurodegenerative process; consequently, there is an urgency to find new therapeutic produc...

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Bibliographic Details
Main Authors: Miriam Corraliza-Gómez, Amalia B. Gallardo, Ana R. Díaz-Marrero, José M. de la Rosa, Luis D’Croz, José Darias, Eduardo Arranz, Irene Cózar-Castellano, María D. Ganfornina, Mercedes Cueto
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Marine Drugs
Subjects:
<i>Leptogorgia</i>
furanocembranolides
leptolide
microglia
astrocytes
gliosis
Online Access:https://www.mdpi.com/1660-3397/18/8/378

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https://www.mdpi.com/1660-3397/18/8/378

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