Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat

Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat

The corpulent JCR:LA-cp rat (cp/cp) is a useful model for study of the metabolic consequences of obesity and hyperinsulinemia. To assess the effect of hyperinsulinemia on VLDL secretion in this model, we measured rates of secretion of VLDL in perfused livers derived from cp/cp rats and their lean li...

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Bibliographic Details
Main Authors: Marshall B. Elam, Henry G. Wilcox, Lauren M. Cagen, Xiong Deng, Rajendra Raghow, Poonam Kumar, Murray Heimberg, James C. Russell
Format: Article
Language:English
Published: Elsevier 2001-12-01
Series:Journal of Lipid Research
Subjects:
animal
cells cultured
liver
obesity
insulin
apolipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520315339

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http://www.sciencedirect.com/science/article/pii/S0022227520315339

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