Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration

Pro-angiogenic and anti-angiogenic peptide hydrogels were evaluated against the standard of care wet age-related macular degeneration (AMD) therapy, Aflibercept (Eylea<sup>®</sup>). AMD was modeled in rats (laser-induced choroidal neovascularization (CNV) model), where the contralateral...

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Bibliographic Details
Main Authors: Amanda Acevedo-Jake, Siyu Shi, Zain Siddiqui, Sreya Sanyal, Rebecca Schur, Simon Kaja, Alex Yuan, Vivek A. Kumar
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/8/12/190