Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness.

Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness.

Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While allosteric inhibition of the mechanistic target of r...

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Bibliographic Details
Main Authors: Gorka Ruiz de Garibay, Carmen Herranz, Alicia Llorente, Jacopo Boni, Jordi Serra-Musach, Francesca Mateo, Helena Aguilar, Laia Gómez-Baldó, Anna Petit, August Vidal, Fina Climent, Javier Hernández-Losa, Álex Cordero, Eva González-Suárez, José Vicente Sánchez-Mut, Manel Esteller, Roger Llatjós, Mar Varela, José Ignacio López, Nadia García, Ana I Extremera, Anna Gumà, Raúl Ortega, María Jesús Plà, Adela Fernández, Sònia Pernas, Catalina Falo, Idoia Morilla, Miriam Campos, Miguel Gil, Antonio Román, María Molina-Molina, Piedad Ussetti, Rosalía Laporta, Claudia Valenzuela, Julio Ancochea, Antoni Xaubet, Álvaro Casanova, Miguel Angel Pujana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4500593?pdf=render

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http://europepmc.org/articles/PMC4500593?pdf=render

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