DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes

DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes

Background & aims: Biliary injury is one of the main pathological mechanisms of fulminant hepatic failure (FHF). Delta-like ligand 4 (DLL4)-mediated Notch activation contributes to reversing biliary injury; however, the specific role of DLL4 in biliary restoration is still unclear. This stud...

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Bibliographic Details
Main Authors: Suwan Sun, Lunzhi Yuan, Zhanglu An, Dongyan Shi, Jiaojiao Xin, Jing Jiang, Keke Ren, Jiaxian Chen, Beibei Guo, Xingping Zhou, Qian Zhou, Xiaojun Jin, Sihan Ruan, Tong Cheng, Ningshao Xia, Jun Li
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Stem Cell Research
Subjects:
Biliary restoration
hBMSC
DLL4
Cholangiocyte differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120302014

Internet

http://www.sciencedirect.com/science/article/pii/S1873506120302014

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