Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade

Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade

The classic sterol regulatory cis element (sre-1) in the LDL receptor promoter mediates sterol regulatory element binding protein (SREBP)-binding and the effects of insulin and platelet derived growth factor (PDGF). To elucidate whether SREBP-1a and SREBP-2 play a direct role in insulin and PDGF act...

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Bibliographic Details
Main Authors: Jörg Kotzka, Dirk Müller-Wieland, Gunther Roth, Lorena Kremer, Martina Munck, Sandra Schürmann, Birgit Knebel, Wilhelm Krone
Format: Article
Language:English
Published: Elsevier 2000-01-01
Series:Journal of Lipid Research
Subjects:
SREBPs
MAP kinase cascade
transcription factors
insulin
growth factors
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520320794

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http://www.sciencedirect.com/science/article/pii/S0022227520320794

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